Rybelsus - glucagon-like peptide-1 receptor (GLP-1) analogs

 By applying a 14% risk reduction, we find that 172 out of 1000 people would experience cardiovascular events instead of 200, meaning the treatment could save 28 people from such events over a 10-year period.

Interpretation over 10 years:

  • Without treatment: 200 out of 1000 people would experience cardiovascular events (20% risk).
  • With treatment (Rybelsus): 172 out of 1000 people would experience cardiovascular events (17.2% risk after a 14% risk reduction).
  • Lives saved: The treatment saves 28 people (200 - 172 = 28) over 10 years, which equals 2.8 lives saved per 1000 treated patients per year.

Exercise and diet:

When it comes to exercise and diet, there is strong scientific evidence that these lifestyle changes can have a powerful impact on reducing the risk of cardiovascular events in people with type 2 diabetes. Studies have shown that regular physical activity and a healthy diet rich in fiber and low in saturated fat can lead to:

  • Improved blood sugar control
  • Lower blood pressure
  • Reduced inflammation
  • Lower cholesterol levels

These lifestyle changes can reduce the risk of cardiovascular events as much as or even more than some medications, depending on how consistently and intensely they are implemented. Some studies have shown risk reductions of up to 30% or more for individuals who undergo significant lifestyle changes.


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